Well, here’s an odd story. Demi-Lee Brennan received a liver transplant, and is now O-positive instead of O-negative as she used to be.
“I was convinced we had made a mistake, so we tested it again and it came up the same. Then we tested her parents and they were both O-negative, so it was confirmed that Demi absolutely had to have been O-negative.”
Dr Curtin said Demi-Lee’s blood then began to break down, requiring more medications.
“We then realised it was her own residual cells which were causing the problem and we needed to get rid of them. And that’s when we knew we had to convince the doctors that Demi’s immuno-suppressant drug regime should be stopped, rather than increased.”
But paediatric nephrologist Stephen Alexander says he wasn't easily convinced.
“We didn’t believe this at first. We thought it was too strange to be true,” Dr Alexander said.
“Normally the body’s own immune system rejects any cells that are transplanted … but for some reason the cells that came from the donor’s liver seemed to survive better than Demi-Lee’s own cells. It has huge implications for the future of organ transplants.”
Demi-Lee, who has now been off all immuno-suppressants for 3½ years, is playing sport and working towards her school certificate. “I feel quite normal. It’s almost like it never happened,” she said yesterday. “I can’t thank the donor’s family enough, and the doctors, for giving me this second chance at life.”
Thanks to my mother for the pointer.
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